The 9th edition of the gold standard in pediatric cardiology offers up-to-date, comprehensive coverage of this challenging and rapidly changing field. New chapters based on reader requests, two new associate editors, new contributing authors, and an enhanced digital version of the text make Moss and Adams’ Heart Disease in Infants, Children, and Adolescents the reference you’ll turn to when caring for patients. From cover to cover, this award-winning two-volume resource provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. * New, reader-requested chapters cover Development of Myocardial Structure and Function, Global Challenge of Heart Disease, Impact of Congenital Heart Disease on Other Organ Systems, Non-Compaction Cardiomyopathy, Beyond the Cardiac Device, and Transition to Adult Care.
* All chapters have been updated and revised, including vital new information on genetics and embryo development.
* Two new associate editors, Drs. Daniel J. Penny and Frank Cetta, offer fresh perspectives in their areas of expertise.
* Enhanced digital access includes the full text; bonus question and answer sections similar to those on the pediatric cardiology board examination; videos of echoes, angiograms, aortic arch anomalies, open-heart operations, and more; and phonocardiograms with accompanying audio of various heart sounds and murmurs.
Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: * Complete content with enhanced navigation
* Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
* Cross-linked pages, references, and more for easy navigation
* Highlighting tool for easier reference of key content throughout the text
* Ability to take and share notes with friends and colleagues
* Quick reference tabbing to save your favorite content for future use

CONTENTS

Contributors
Preface
Tribute to Moss, Adams, and Emmanouilides
History of Pediatric Cardiology
Hugh D. Allen, Daniel J. Penny, and Charles D. Fraser
The Development of Pediatric Cardiology: Historical Milestones Available in eBook edition
George C. Emmanouilides

Section I. From the Gene to the Neonate
1. Development of the Heart: Morphogenesis, Growth, and Molecular Regulation of Differentiation
Aleksander Sizarov, H. Scott Baldwin, Deepak Srivastava, and Antoon F.M. Moorman
2. Epidemiology and Prevention of Congenital Heart Defects
Lorenzo D. Botto
3. Genetics of Congenital Heart Defects
Elizabeth Goldmuntz and Melissa L. Crenshaw
4. Development of Myocardial Structure and Function
Pamela A. Lucchesi, Aaron J. Trask, Rachel C. Childers, and Richard L. Goodwin
5. Fetal and Perinatal Cardiology
Shaine A. Morris, Shiraz A. Maskatia, Carolyn A. Altman, and Nancy A. Ayres
Section II. Structure and Function of the Cardiovascular System
6. Cardiac Anatomy and Examination of Cardiac Specimens
Joseph J. Maleszewski and William D. Edwards
7. Classification and Terminology of Cardiovascular Anomalies
Joseph J. Maleszewski and William D. Edwards
8. Cardiovascular Physiology
Daniel J. Penny and Ronald A. Bronicki
Section III. Diagnostic and Therapeutic Methods
9. History and Physical Examination
Steven C. Cassidy, Hugh D. Allen, and John R. Phillips
10. Exercise Screening and Sports Participation
Julie A. Brothers, Paul Stephens, Jr., and Stephen M. Paridon
11. Exercise Testing
Paolo T. Pianosi and David J. Driscoll
12. Echocardiography: Basic Principles and Imaging
Haleh C. Heydarian and Thomas R. Kimball
13. Echocardiographic Assessment of Cardiac Dimensions, Cardiac Function, and Valve Function
Luc L. Mertens and Mark K. Friedberg
14. Magnetic Resonance Imaging
Tal Geva and Andrew J. Powell
15. Cardiac Computed Tomography in Children with Congenital Heart Disease
Rajesh Krishnamurthy, Farahnaz Golriz, and Siddharth Jadhav
16. Cardiac Catheterization and Angiography
Nathaniel W. Taggart and Allison K. Cabalka
17. Therapeutic Cardiac Catheterization
Ralf J. Holzer and John P. Cheatham
Section IV. Electrophysiology
18. Development and Functional Maturation of the Cardiac Conduction System
Aleksander Sizarov, Antoon F.M. Moorman, and Arthur S. Pickoff
19. The Normal Electrocardiogram
George F. Van Hare and Jennifer N.A. Silva
20. Cardiac Channelopathies, Syncope, and Sudden Death
David J. Tester and Michael J. Ackerman
21. Electrophysiology Studies and Electrophysiologic Therapeutic Catheterization
J. Philip Saul and John D. Kugler
22. Disorders of Cardiac Rhythm and Conduction
Bryan C. Cannon and Christopher S. Snyder
Section V. Pediatric Cardiac Intensive Care
23. Physiology of the Preterm and Term Infant
Timothy M. Hoffman and Stephen E. Welty
24. Cardiovascular Intensive Care
Dean B. Andropoulos, Lara S. Shekerdemian, Paul A. Checchia, and Anthony C. Chang
25. Mechanical Circulatory Support in Children
Aamir Jeewa, Iki Adachi, and Jack Price
26. Cardiopulmonary and Right-Left Heart Interactions
Andrew N. Redington
27. Cardiac Trauma
Gary A. Smith and Timothy F. Feltes
Section VI: Congenital Cardiovascular Malformations
Part A. Septal Defects
28.Atrial Septal Defects
Ritu Sachdeva
29. Atrioventricular Septal Defects
Frank Cetta, Dongngan Truong, L. Luann Minich, Joseph J. Maleszewski, Patrick W. O’Leary, Joseph A. Dearani, and Harold M. Burkhart
30. Ventricular Septal Defects
Meryl S. Cohen and Leo Lopez
Part B. Arterial Abnormalities
31. Patent Ductus Arteriosus and Aortopulmonary Window
Nathaniel W. Taggart and Mohammed Yasir Qureshi
32. Congenital Anomalies of the Coronary Vessels and the Aortic Root
D. Scott Lim and G. Paul Matherne
33. Aortic Arch and Vascular Anomalies
David S. Ezon and Daniel J. Penny
34. Abnormalities of the Aortic Root
Matina Prapa, John Pepper, and Michael A. Gatzoulis
Part C. Venous Abnormalities
35. Anomalies of the Pulmonary Veins
David W. Brown and Tal Geva
36. Abnormal Systemic Venous Connections
Tal Geva
37. Vascular Tumors and Anomalies
Ahmad I. Alomari
Part D. The Right Ventricle
38. Tricuspid Valve Disorders: Atresia, Dysplasia, and Ebstein Anomaly
Frank Cetta, Joseph A. Dearani, Patrick W. O’Leary, and David J. Driscoll
39. Pulmonary Stenosis
Lourdes R. Prieto and Larry A. Latson
40. Pulmonary Atresia and Intact Ventricular Septum
David G. Nykanen
41. Tetralogy of Fallot with Pulmonary Stenosis, Pulmonary Atresia, and Absent Pulmonary Valve
S. Lucy Roche, Steven C. Greenway, and Andrew N. Redington
42. Truncus Arteriosus
Allison K. Cabalka, William D. Edwards, and Joseph A. Dearani
Part E. Left Ventricular Inflow and Outflow Abnormalities
43. Mitral Inflow Obstruction and Mitral Regurgitation, Including Mitral Valve Prolapse
Mackie, Smallhorn
44. Aortic Stenosis
Joshua M. Friedland-Little, Jeffrey D. Zampi, and Robert J. Gajarski
45. Coarctation of the Aorta
Robert H. Beekman III
46. Hypoplastic Left Heart Syndrome
James S. Tweddell, George M. Hoffman, Nancy S. Ghanayem, Michele A. Frommelt, Kathleen A. Mussatto, and Stuart Berger
Part F. Abnormalities of the Origin of the Great Arteries
47. Transposition of the Great Arteries
Athar M. Qureshi, Henri Justino, and Jeffrey S. Heinle
48. Congenitally Corrected Transposition of the Great Arteries (Atrioventricular and Ventriculoarterial Discordance)
Joseph Atallah, Jennifer M. Rutledge, and John D. Dyck
49. Double-Outlet Right Ventricle
Gail E. Wright, Katsuhide Maeda, Norman H. Silverman, Frank L. Hanley, and Stephen J. Roth
Part G. Complex Cardiac Abnormalities
50. Univentricular Atrioventricular Connection
Michael G. Earing, Donald J. Hagler, and William D. Edwards
51. Cardiac Malpositions and Abnormalities of Atrial and Visceral Situs
Patrick W. O'Leary, Muhammad Yasir Qureshi, Donald J. Hagler
Section VII. Diseases of the Endocardium, Myocardium, and Pericardium
52. Hypertrophic Cardiomyopathy
Barry J. Maron
53. Dilated Cardiomyopathy
Kimberly Y. Lin and Joseph W. Rossano
54. Left Ventricular Noncompaction Cardiomyopathy
Colin J. McMahon and Ricardo H. Pignatelli
55. Myocarditis
Kathleen E. Simpson, Shafkat Anwar, and Charles E. Canter
56. Restrictive Cardiomyopathy
Susan W. Denfield
57. The Heart in the Muscular Dystrophies
Philip T. Thrush, Jerry R. Mendell, Kevin M. Flanigan, Timothy M. Hoffman, and Hugh D. Allen
58. Kawasaki Disease (Mucocutaneous Lymph Node Syndrome)
Sarah D. de Ferranti, Jane C. Burns, and Jane W. Newburger
59. Rheumatic Fever and Rheumatic Heart Disease
Lloyd Y. Tani
60. Inflammatory Noninfectious Cardiovascular Diseases
Carolyn A. Altman, William B. Kyle, Kristen Sexson Tejtel, Marietta M. DeGuzman, Santiago Valdes, and Andrea Ramirez
61. Pericardial Diseases
Jonathan N. Johnson and Frank Cetta
62. Infective Endocarditis and Prevention
Michael Gewitz and Kathryn A. Taubert
63. Myocardial Ischemia in the Pediatric Population
Ali N. Zaidi and Curt J. Daniels
64. Pediatric Heart Transplantation
Robert E. Shaddy and Francesco Parisi
Section VIII. Pulmonary Vascular Disease
65. Pathophysiology of Pulmonary Hypertension
Marlene Rabinovitch and Rachel K. Hopper
66. Pediatric Pulmonary Hypertension
Dunbar Ivy
Section IX. Unique Issues Regarding the Young Adult with Congenital Heart Disease
67. The Adolescent and Adult with Congenital Heart Disease
Ali N. Zaidi and Curt J. Daniels
68. Transition to Adult Care
Peter R. Ermis and Wayne J. Franklin
69. Pregnancy in Young Women with Congenital Heart Disease
Candice Silversides, Jack M. Colman, and Samuel C. Siu
Section X. Other Special Problems and Issues
70. Chest Pain in Children and Adolescents
Jonathan N. Johnson and David J. Driscoll
71. Coronary Risk Factors in Children
Stephen R. Daniels
72. Cardiac Tumors
Gerald Ross Marx and Adrian M. Moran
73. Chronic Heart Failure in Children
Matthew J. O’Connor and Robert E. Shaddy
74. Neurodevelopmental Outcomes After Heart Surgery in Children
Caren S. Goldberg and Jane W. Newburger
75. Hematologic Aspects of Pediatric and Adolescent Heart Disease: Bleeding, Clotting, and Blood Component Abnormalities
Therese M. Giglia and Char Witmer
76. Impact of Cardiac Disease on Other Organ Systems
Jack Rychik
77. Evaluation of Quality of Life in Children and Adolescents with Congenital and Acquired Heart Disease
Bradley S. Marino
78. Beyond the Cardiac Device: Comprehensive Care of Children and Young Adults with Implantable Cardiac Devices
Caridad M. de la Uz, Katherine Elizabeth Cutitta, and Samuel F. Sears Jr.
79. Safety and Quality in the Heart Center
Anthony Y. Lee, Tom Taghon, Richard McClead, Wallace Crandall, Terrance Davis, and Richard J. Brilli
80. The Global Challenge of Heart Disease
Daniel J. Penny, Jonathan R. Carapetis, and Peter J. Hotez
81. Design, Execution, and Appraisal of Clinical Trials
Brian W. McCrindle
82. Pharmacology
Jonathan B. Wagner, Gregory L. Kearns, and Michale Artman